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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP4C
All Species:
56.06
Human Site:
Y134
Identified Species:
88.1
UniProt:
P60510
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P60510
NP_002711.1
307
35080
Y134
Y
D
E
C
L
R
K
Y
G
S
V
T
V
W
R
Chimpanzee
Pan troglodytes
XP_001148385
265
30391
Q122
H
E
S
R
Q
I
T
Q
V
Y
G
F
Y
D
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_858953
324
36761
Y134
Y
D
E
C
L
R
K
Y
G
S
V
T
V
W
R
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Q5BJ92
307
35049
Y134
Y
D
E
C
L
R
K
Y
G
S
V
T
V
W
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505222
306
34933
Y133
Y
D
E
C
L
R
K
Y
G
S
V
T
V
W
R
Chicken
Gallus gallus
P48463
309
35545
Y137
Y
D
E
C
L
R
K
Y
G
N
A
N
V
W
K
Frog
Xenopus laevis
Q6IP91
307
35104
Y134
Y
D
E
C
L
R
K
Y
G
S
V
T
V
W
R
Zebra Danio
Brachydanio rerio
A9JRC7
307
35078
Y134
Y
D
E
C
L
R
K
Y
G
S
V
T
V
W
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O76932
307
35323
Y134
Y
D
E
C
L
R
K
Y
G
S
T
A
V
W
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9XW79
333
37341
Y159
Y
D
E
C
L
R
K
Y
G
N
A
S
V
W
K
Sea Urchin
Strong. purpuratus
XP_799172
307
35031
Y134
Y
D
E
C
L
R
K
Y
G
S
I
T
V
W
R
Poplar Tree
Populus trichocarpa
XP_002317353
305
34758
Y131
Y
D
E
C
L
R
K
Y
G
S
V
N
V
W
R
Maize
Zea mays
NP_001170721
307
34933
Y133
Y
D
E
C
L
R
K
Y
G
S
V
N
V
W
R
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P48528
305
34707
Y131
Y
D
E
C
L
R
K
Y
G
S
V
N
V
W
R
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48580
327
37273
Y155
Y
D
E
C
L
R
K
Y
G
N
A
N
V
W
K
Conservation
Percent
Protein Identity:
100
86.3
N.A.
94.7
N.A.
N.A.
99.6
N.A.
91.2
66
99
98
N.A.
91.5
N.A.
74.7
93.4
Protein Similarity:
100
86.3
N.A.
94.7
N.A.
N.A.
99.6
N.A.
92.5
81.2
99.6
99.6
N.A.
96.4
N.A.
82.5
97
P-Site Identity:
100
0
N.A.
100
N.A.
N.A.
100
N.A.
100
73.3
100
100
N.A.
86.6
N.A.
73.3
93.3
P-Site Similarity:
100
13.3
N.A.
100
N.A.
N.A.
100
N.A.
100
86.6
100
100
N.A.
86.6
N.A.
93.3
100
Percent
Protein Identity:
82
81.4
N.A.
82
N.A.
60.8
Protein Similarity:
89.9
90.8
N.A.
90.5
N.A.
75.8
P-Site Identity:
93.3
93.3
N.A.
93.3
N.A.
73.3
P-Site Similarity:
93.3
93.3
N.A.
93.3
N.A.
86.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
20
7
0
0
0
% A
% Cys:
0
0
0
94
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
94
0
0
0
0
0
0
0
0
0
0
0
7
0
% D
% Glu:
0
7
94
0
0
0
0
0
0
0
0
0
0
0
7
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
94
0
7
0
0
0
0
% G
% His:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
7
0
0
0
0
7
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
94
0
0
0
0
0
0
0
20
% K
% Leu:
0
0
0
0
94
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
20
0
34
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
7
0
0
7
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
7
0
94
0
0
0
0
0
0
0
0
74
% R
% Ser:
0
0
7
0
0
0
0
0
0
74
0
7
0
0
0
% S
% Thr:
0
0
0
0
0
0
7
0
0
0
7
47
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
7
0
60
0
94
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
94
0
% W
% Tyr:
94
0
0
0
0
0
0
94
0
7
0
0
7
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _